Vasoactol is a nutritional supplement used to complement the daily diet for people who are in special physiological conditions, middle-aged or elderly people, and also those who require special physical efforts. It is also useful in cases of fat metabolism disorders.  

      Vasoactol is isolated from the wax that covers the sugar cane´s stem and it presents a special composition. Its main components are insaturated and saturated fat acids and high molecular weight alcohols. This composition makes Vasoactol  be a possible suplement for the daily diet and allows to satisfy the personal needs of who show special physiological conditions,  disorders in their process of assimilation and in their metabolism.  

      It has been shown, in experiences by using an ergometric bicycle, that Vasoactol increases the physical efficiency in elderly people and it also produces good results for their health conditions, often affected by dysfunctions related with physioligical equilibrium disorders of the elders. Similar results have been also founded  in middle-aged groups with physical attitions and in some groups that play sports. 
  
      Vasoactol also has antioxide effects, through which resists the negative influence that over the  physiological equilibrium and the metabolism could play the processes of oxidezing stress. 

      The sugar cane (Saccharum officinarum) presents a long stem  with  green or yellowish spongy internode. This is the part from where we take the saccharose. the leaves and the external part of the stem are covered by wax from which the Vasoactol is obtained.  

      The vegetal waxes play the role of proteccion and restoration of the vegetable´s function,  as  controling the loose of water, preventing the mechanical deterioration of the leaves and the integral guarantee of the vegetable growth.⁽⁴⁾  
Among the main components of the waxes there are fat acids and superior primary  aliphatic alcohols. Therefore all these ingredients  are included in Vasoactol's components.  

      The fat acids are  long hydrocarboned chains that have a carboxyl group and they can be saturated and insaturated. Within the saturated fat acids, all carbon atoms joined as many hydrogen atoms as possible. The insaturated fat acids contains  carbon atoms united by doubles lacings; such carbon atoms can develop additional  lacings with other atoms ( that is why it is called insaturated).  

      The superior primary aliphatic alcohols are long hydrocarbon chains that generally contents from 24 to 32 carbon atoms  that have a hydroxil terminal. Its presence within plants has been relationed with nutritional functions needed by the vegetable during its growth,  such as the regulation of the vegetable growth.^(5-8)  

3) PHYSIOLOGICAL ACTIONS AND COMPONENTS´REQUIRES  

      Human requirements´studies of these composites have proved that the lack of insaturated acid fats in the daily diet carries out different disorders.  
In that sense, some works have revealed the need of these acids in the diet in order to have a good maintenance of many functions. Among them stand out those related with the central nervious system (CNS) and its cognitive functions. ^(9-15) In the same way, the presence of large chain alcohols is a very important aspect to the develop of the CNS, where it can even be metabolizer.^(16-l9)   

      The consequences, that the lack of these nutrients causes, are related to different metabolic dysfunctions. That is why by adding  a proportion of vegetable origined waxes to your daily diet you correct, according to what it is possible, an extended need and you prevent its negative consequences over the metabolism. By taking Vasoactol you are complementing your daily diet with elements from a diet that it is rich in fruits and that includes the supplement of its original tegument.  
   
     So,Vasoactol plays different actions that are good for the matabolism:  
 
• As it has been referred, studies done with elderly people have proved that Vasoactol increases the physic efficiency within elderly people that have been taking test with egometric bicycles. It has been  also proved that those effects go with a general  improvement of their health.  This improvement is an important aspect of their life quality of these people that suffer common and profuse disturbances and they affect in some ways their activities. 

• Such effects  are also good for those middle-aged groups and people that play sports. The equilibrium between the assimilation process and attrition, represents an antechamber that helps, a more or less, favourable quality of life evolution at this stage and fiurther.  

• On the other hand, Vasoactol shows  antioxidants effects that contribute to counteract the actions that over the functional equilibrium induce the oxidize stress processes and the production of  free radicals.  

4) TOLERANCE & SECURITY  

      Vasoactol is a safety and well tolerated product. Untill now, there has not been proved advers effects  attributable to its consumption.  
  
5) PRESENTATION  

      Boxes containing 3 blisters with 10 tablets each one.  

6) CONSUMING ORIENTATION  

     1 or 2 tablets per day during meals.  

7) ALLEGATIONS  

• Nutritional supplement for special physical effects & physical attrition.  

• Nutritional supplement for sports.  

• Nutritional supplement for elderly people.  

8)  CONSERVATION TIME  

      3 years from fabrication date keeping it in right conditions.  
  

9) STORAGE CONDITIONS  

      Keep it in dry and fresh place, ambient temperature. It does not requires special conditions for its conservation.  

10) BIBLIOGRAPHY  

1. RAVEN, H.P.; EVERT, R.F.; EICHHORN, S.E. Biología de las plantas. Ed. Reverte, Barcelona, 1991.  

2. BALANDRIN, MANUEL F. et al. Natural Plant Chemicals Sources of Industrial and Medicinal Materials. Science 228: 1 145-1 160; 1984.  

3. BOARD OF SCIENCE AND TECHNOLOGY FOR INTERNATIONAL DEVELOPMENT, NATIONAL RESEARCH COUNCIL. Unexplored Tropical Plants with Promising Economic Value, National Acad. Press, Washington, D.C. 1975.  

4. SPENCER R.S., CHAPMAN G.W. Surface wax of Coastal Bermuda Grass. J. Agric. Food Chem., 33: 656-663, 1985.  

5. RIES S.K. Regulation of plant growth with triacontanol. CRC Crit. Rev. Plant Sci. 2: 654-662, 1985.  

6. RIES S.K., HOUTZ R.L. Triacontanol as a plant growth regulator. Hortic. Sci. 18: 654-662, 1985.  

7. RIES S.K., WERT V.F., SWEELEY C.C., LEAVITT R.A. Triacontanol: A new naturally occurring plant growth regulator. Science 195: 1 339-1 341, 1983.  

8. HOUTZ R.L., RIES S.K., TOLBERT N.E. Effect of triacontanol on Chlamydomonas. I. Stimulation of growth and photosynthetic C02 assimilation. Plant Physiol., 79: 357-364, 1985.  

9. BAZAN N.G. Supply of n-3 polyunsaturated fatty acids and their significance in the central nervous system. In: Wurtman R.J., Wurtman J.J., eds. Nutrition and the brain. Vol. 8, Ncw York: Raven Press, 1: 1990.  

10. BOURRE J.M., DURAND G., PASCAL G. ET AL. Brain cell and tissue recovery in rats made deficient in n-3 fatty acids by alteration of dietary fat. J. Nutr. 15: 119, 1989.  

11. BOURRE J.M., FRANCOIS M., YOUYOU A. ET AL. The effects of dietary a-linoleic acid on the composition of nerve membranas, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J. Nutr. 119: 1880, 1989.  

12. LAMPTEY M.S., WALKER B.L. A possible essential role for dietary linolenic acid in the development of the young rat. J. Nutr. 106: 86, 1976.  

13. YAMAMOTO N., SAITOH M., MORIUCHI A. ET AL. Effect of dielary a-linolenate/linoleate balance on brain compositions and learning ability of rats. J. Lipid Res., 24: 151, 1987.  

14. YAMAMOTO N., HASHIMOTO A. TAKEMOTO Y. ET AL. Effect of the dietary a-linolenate/linoleate balance on lipid compositions and learning ability of rats. II. Discrimination process, extinction process, and glycolipid compositions. J. Lipid Res.; 29: 1013,1988.  

15. CRAWFORD M.A. The role of essential fatty acids in neural development: implications for perinatal nutrition. Am. J. Clin. Nutr., 57: (5 suppl.) 703S-709S, 1993.  

16. ENSLEN M., MILON H., MALONE A.;Effect of low intake of n-3 fatty acids during development on brain phospholipid fatty acid composition and exploratory behavior in rats. Lipids, 26: 203, 1991.  

17. BISHOP J.E., HAYRA A.K. Mechanism and specificity of formulation of long-chain alcohols by developing rat brain. J. Biol. Chern. 256: 9 542-9 5S0, 1981.  

l8. NATARAJAN V., SCHMlD H.H.O., SASTRY P.S. Biosynthesis of long chain alcohols by developing brain and regenerating sciatic nerve. J. Neurochem, 43: 328-334, 1984.  

19. BORG J., TOAZARA J., HIETTER H., HENRY M., SCHMllT G., LUU B. Neurotrophic effect of naturally occurring long-chain fatty alcohols on cultured CNS neurons. FEBS Letters 213: 406-410, 1987.